Microstreaming induced by acoustic bubbles for sonoporation
When a bubble is driven by an acoustic wave, the bubble may begin to oscillate stably under certain conditions. When an excitation threshold is reached, surface modes appear and deform the interface of the bubble, leading to a fluid displacement in its surroundings. This mean flow is called microstreaming. Microstreaming seems to play a key role in the development of tomorrow’s therapeutic treatments like sonoporation. Indeed, the microstreaming could induce a wall shear stress that could temporarily open biological barriers and allow targeted drug delivery. The optimization of such treatments requires a better understanding of the microstreaming process and of the acoustic wave/bubble/biological barrier interaction.
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